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Targeting B cells in treatment of autoimmunity

B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which the ultimate effectors are antibodies, as well as those in which T cells are primary drivers of inflammation. Proof of this principle has come primarily from studies of the efficacy of Rituximab, an ant...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Franks, S Elizabeth, Getahun, Andrew, Hogarth, P Mark, Cambier, John C
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127449/
https://ncbi.nlm.nih.gov/pubmed/27718447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.09.003
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