Whole Genome and Transcriptional Analysis of Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer Demonstrates Intra-class Heterogeneity

Therapeutic resistance in metastatic castration resistant prostate cancer (mCRPC) can be accompanied by treatment-emergent small cell neuroendocrine carcinoma (t-SCNC), a morphologically distinct subtype. We performed integrative whole-genome and -transcriptome analysis of mCRPC tumor biopsies inclu...

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Udgivet i:Mol Cancer Res
Main Authors: Aggarwal, Rahul R., Quigley, David A., Huang, Jiaoti, Zhang, Li, Beer, Tomasz M., Rettig, Matthew B., Reiter, Rob E., Gleave, Martin E., Thomas, George V., Foye, Adam, Playdle, Denise, Lloyd, Paul, Chi, Kim N., Evans, Christopher P., Lara, Primo N., Feng, Felix Y., Alumkal, Joshi J., Small, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548614/
https://ncbi.nlm.nih.gov/pubmed/30918106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1101
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