Whole Genome and Transcriptional Analysis of Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer Demonstrates Intra-class Heterogeneity

Therapeutic resistance in metastatic castration resistant prostate cancer (mCRPC) can be accompanied by treatment-emergent small cell neuroendocrine carcinoma (t-SCNC), a morphologically distinct subtype. We performed integrative whole-genome and -transcriptome analysis of mCRPC tumor biopsies inclu...

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Bibliografiset tiedot
Julkaisussa:Mol Cancer Res
Päätekijät: Aggarwal, Rahul R., Quigley, David A., Huang, Jiaoti, Zhang, Li, Beer, Tomasz M., Rettig, Matthew B., Reiter, Rob E., Gleave, Martin E., Thomas, George V., Foye, Adam, Playdle, Denise, Lloyd, Paul, Chi, Kim N., Evans, Christopher P., Lara, Primo N., Feng, Felix Y., Alumkal, Joshi J., Small, Eric J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548614/
https://ncbi.nlm.nih.gov/pubmed/30918106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1101
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