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Whole Genome and Transcriptional Analysis of Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer Demonstrates Intra-class Heterogeneity

Therapeutic resistance in metastatic castration resistant prostate cancer (mCRPC) can be accompanied by treatment-emergent small cell neuroendocrine carcinoma (t-SCNC), a morphologically distinct subtype. We performed integrative whole-genome and -transcriptome analysis of mCRPC tumor biopsies inclu...

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Опубликовано в: :Mol Cancer Res
Главные авторы: Aggarwal, Rahul R., Quigley, David A., Huang, Jiaoti, Zhang, Li, Beer, Tomasz M., Rettig, Matthew B., Reiter, Rob E., Gleave, Martin E., Thomas, George V., Foye, Adam, Playdle, Denise, Lloyd, Paul, Chi, Kim N., Evans, Christopher P., Lara, Primo N., Feng, Felix Y., Alumkal, Joshi J., Small, Eric J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548614/
https://ncbi.nlm.nih.gov/pubmed/30918106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1101
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