Whole Genome and Transcriptional Analysis of Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer Demonstrates Intra-class Heterogeneity

Therapeutic resistance in metastatic castration resistant prostate cancer (mCRPC) can be accompanied by treatment-emergent small cell neuroendocrine carcinoma (t-SCNC), a morphologically distinct subtype. We performed integrative whole-genome and -transcriptome analysis of mCRPC tumor biopsies inclu...

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Publicat a:Mol Cancer Res
Autors principals: Aggarwal, Rahul R., Quigley, David A., Huang, Jiaoti, Zhang, Li, Beer, Tomasz M., Rettig, Matthew B., Reiter, Rob E., Gleave, Martin E., Thomas, George V., Foye, Adam, Playdle, Denise, Lloyd, Paul, Chi, Kim N., Evans, Christopher P., Lara, Primo N., Feng, Felix Y., Alumkal, Joshi J., Small, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548614/
https://ncbi.nlm.nih.gov/pubmed/30918106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1101
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