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cGAS-independent STING activation in response to DNA damage
Self-DNA has previously been thought to be protected from immune detection by compartmentalisation in the nucleus or mitochondria. Here, we describe the discovery of a signalling cascade that links the detection of DNA damage in the nucleus to the activation of the innate immune adaptor STING (STimu...
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| Veröffentlicht in: | Mol Cell Oncol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548478/ https://ncbi.nlm.nih.gov/pubmed/31211228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1558682 |
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