Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus

Eukaryotic genomes are packaged into a three-dimensional structure in the nucleus. Current methods for studying genome-wide structure are based on proximity-ligation. However, this approach can fail to detect known structures, such as interactions with nuclear bodies, because these DNA regions can b...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Quinodoz, Sofia A., Ollikainen, Noah, Tabak, Barbara, Palla, Ali, Schmidt, Jan Marten, Detmar, Elizabeth, Lai, Mason M., Shishkin, Alexander A., Bhat, Prashant, Takei, Yodai, Trinh, Vickie, Aznauryan, Erik, Russell, Pamela, Cheng, Christine, Jovanovic, Marko, Chow, Amy, Cai, Long, McDonel, Patrick, Garber, Manuel, Guttman, Mitchell
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548320/
https://ncbi.nlm.nih.gov/pubmed/29887377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.024
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