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Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus

Eukaryotic genomes are packaged into a three-dimensional structure in the nucleus. Current methods for studying genome-wide structure are based on proximity-ligation. However, this approach can fail to detect known structures, such as interactions with nuclear bodies, because these DNA regions can b...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell
Κύριοι συγγραφείς: Quinodoz, Sofia A., Ollikainen, Noah, Tabak, Barbara, Palla, Ali, Schmidt, Jan Marten, Detmar, Elizabeth, Lai, Mason M., Shishkin, Alexander A., Bhat, Prashant, Takei, Yodai, Trinh, Vickie, Aznauryan, Erik, Russell, Pamela, Cheng, Christine, Jovanovic, Marko, Chow, Amy, Cai, Long, McDonel, Patrick, Garber, Manuel, Guttman, Mitchell
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548320/
https://ncbi.nlm.nih.gov/pubmed/29887377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.024
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