Metformin Induces Apoptosis and Inhibits Proliferation through the AMP-Activated Protein Kinase and Insulin-like Growth Factor 1 Receptor Pathways in the Bile Duct Cancer Cells

Background/Aims: Metformin has been found to have antineoplastic activity in some cancer cells. This study was performed to determine whether metformin inhibits the proliferation of bile duct cancer cells by inducing apoptosis and its effects on the expression of gene-related proteins involved in ca...

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Publicat a:J Cancer
Autors principals: Lee, Jin, Hong, Eun Mi, Kim, Jung Han, Jung, Jang Han, Park, Se Woo, Koh, Dong Hee, Choi, Min Ho, Jang, Hyun Joo, Kae, Sea Hyub
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547996/
https://ncbi.nlm.nih.gov/pubmed/31205529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.26380
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