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Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells

BACKGROUND/AIMS: Statins act as antineoplastic agents through the inhibition of cell proliferation. This study sought to demonstrate the effects of statins on extrahepatic bile duct cancer cell apoptosis and to document the changes in protein expression involved in tumor growth and suppression. METH...

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Detalhes bibliográficos
Publicado no:Gut Liver
Main Authors: Lee, Jin, Hong, Eun Mi, Jang, Ju Ah, Park, Se Woo, Koh, Dong Hee, Choi, Min Ho, Jang, Hyun Joo, Kae, Sea Hyub
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Office of Gut and Liver 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780463/
https://ncbi.nlm.nih.gov/pubmed/26470769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl15195
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