Synergistic Effects of Simvastatin and Irinotecan against Colon Cancer Cells with or without Irinotecan Resistance

Aims. We here investigated whether the combination of simvastatin and irinotecan could induce the synergistic effect on colon cancer cells with or without resistance to irinotecan. Methods. We investigated cell proliferation assay and assessed cell death detection ELISA and caspase-3 activity assay...

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Vydáno v:Gastroenterol Res Pract
Hlavní autoři: Jang, Hyun Joo, Hong, Eun Mi, Jang, Juah, Choi, Jung Eun, Park, Se Woo, Byun, Hyun Woo, Koh, Dong Hee, Choi, Min Ho, Kae, Sea Hyub, Lee, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757714/
https://ncbi.nlm.nih.gov/pubmed/26966430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7891374
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