Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation

Enhancer of zeste homolog 2 (EZH2)-mediated trimethylation of histone 3 lysine 27 (H3K27Me3) is critical for immune regulation. However, evidence is lacking to address the effect of EZH2 enzyme’s activity on intestinal immune responses during inflammatory bowel disease (IBD). Here we report that sup...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Zhou, Jie, Huang, Shuo, Wang, Zhongyu, Huang, Jiani, Xu, Liang, Tang, Xuefeng, Wan, Yisong Y., Li, Qi-jing, Symonds, Alistair L. J., Long, Haixia, Zhu, Bo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547712/
https://ncbi.nlm.nih.gov/pubmed/31160593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10176-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars