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Smyd2 conformational changes in response to p53 binding: role of the C‐terminal domain

Smyd2 lysine methyltransferase regulates monomethylation of histone and nonhistone lysine residues using S‐adenosylmethionine cofactor as the methyl donor. The nonhistone interactors include several tumorigenic targets, including p53. Understanding this interaction would allow the structural princip...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Chandramouli, Balasubramanian, Melino, Gerry, Chillemi, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547616/
https://ncbi.nlm.nih.gov/pubmed/31069954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12502
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