Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study

IMPORTANCE: Positron emission tomography (PET) imaging now allows in vivo visualization of both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau neurofibrillary tangles. Observing their progressive accumulation in the brains of clinically normal older adults is cri...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Hanseeuw, Bernard J., Betensky, Rebecca A., Jacobs, Heidi I. L., Schultz, Aaron P., Sepulcre, Jorge, Becker, J. Alex, Cosio, Danielle M. Orozco, Farrell, Michelle, Quiroz, Yakeel T., Mormino, Elizabeth C., Buckley, Rachel F., Papp, Kathryn V., Amariglio, Rebecca A., Dewachter, Ilse, Ivanoiu, Adrian, Huijbers, Willem, Hedden, Trey, Marshall, Gad A., Chhatwal, Jasmeer P., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547132/
https://ncbi.nlm.nih.gov/pubmed/31157827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.1424
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