Lataa...
Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling
RIF1 is a multifunctional protein implicated in controlling DNA replication and repair. Here, we show that human RIF1 protects nascent DNA from over-degradation at stalled replication forks. The major nuclease resecting nascent DNA in the absence of RIF1 is DNA2, operating with WRN as an accessory h...
Tallennettuna:
| Julkaisussa: | Cell Rep |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cell Press
2019
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547018/ https://ncbi.nlm.nih.gov/pubmed/31141682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.002 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|