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Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility

Modern genetic studies indicate that human brain evolution is driven primarily by changes in gene regulation, which requires understanding the biological function of largely non-coding gene regulatory elements, many of which act in tissue specific manner. We leverage chromatin interaction profiles i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Won, Hyejung, Huang, Jerry, Opland, Carli K., Hartl, Chris L., Geschwind, Daniel H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546784/
https://ncbi.nlm.nih.gov/pubmed/31160561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10248-3
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