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Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility

Modern genetic studies indicate that human brain evolution is driven primarily by changes in gene regulation, which requires understanding the biological function of largely non-coding gene regulatory elements, many of which act in tissue specific manner. We leverage chromatin interaction profiles i...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Won, Hyejung, Huang, Jerry, Opland, Carli K., Hartl, Chris L., Geschwind, Daniel H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546784/
https://ncbi.nlm.nih.gov/pubmed/31160561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10248-3
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