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NV-5138 as a fast-acting antidepressant via direct activation of mTORC1 signaling
Growing evidence implicates altered mTORC1 signaling cascades in the pathophysiology of depression, suggesting that direct modulation of mTORC1 signaling may offer novel therapeutic potential. In this issue of the JCI, Kato and colleagues reported that administration of NV-5138, a recently developed...
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| Published in: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546442/ https://ncbi.nlm.nih.gov/pubmed/31107245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129702 |
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