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Defining the seed sequence of the Cas12b CRISPR-Cas effector complex
Target binding by CRISPR-Cas ribonucleoprotein effectors is initiated by the recognition of double-stranded PAM motifs by the Cas protein moiety followed by destabilization, localized melting, and interrogation of the target by the guide part of CRISPR RNA moiety. The latter process depends on seed...
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| Pubblicato in: | RNA Biol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546406/ https://ncbi.nlm.nih.gov/pubmed/30022698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1495492 |
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