Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding

Bats are natural reservoir hosts, harboring more than 100 viruses, some of which are lethal to humans. The asymptomatic coexistence with viruses is thought to be connected to the unique immune system of bats. MHC class I (MHC I) presentation is closely related to cytotoxic lymphocyte immunity, which...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Qu, Zehui, Li, Zibin, Ma, Lizhen, Wei, Xiaohui, Zhang, Lijie, Liang, Ruiying, Meng, Geng, Zhang, Nianzhi, Xia, Chun
Format: Artigo
Langue:Inglês
Publié: AAI 2019
Sujets:
Molecular and Structural Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545463/
https://ncbi.nlm.nih.gov/pubmed/31076531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900001
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