Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding

Bats are natural reservoir hosts, harboring more than 100 viruses, some of which are lethal to humans. The asymptomatic coexistence with viruses is thought to be connected to the unique immune system of bats. MHC class I (MHC I) presentation is closely related to cytotoxic lymphocyte immunity, which...

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Bibliographic Details
Published in:J Immunol
Main Authors: Qu, Zehui, Li, Zibin, Ma, Lizhen, Wei, Xiaohui, Zhang, Lijie, Liang, Ruiying, Meng, Geng, Zhang, Nianzhi, Xia, Chun
Format: Artigo
Language:Inglês
Published: AAI 2019
Subjects:
Molecular and Structural Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545463/
https://ncbi.nlm.nih.gov/pubmed/31076531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900001
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