Illumination of PRRSV Cytotoxic T Lymphocyte Epitopes by the Three-Dimensional Structure and Peptidome of Swine Lymphocyte Antigen Class I (SLA-I)

To investigate CTL epitope applications in swine, SLA-1(*)1502-restricted peptide epitopes matching porcine reproductive and respiratory syndrome virus (PRRSV) strains were explored by crystallography, biochemistry, and the specific pathogen-free (SPF) swine experiments. First, nine predicted PRRSV...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pan, Xiaocheng, Zhang, Nianzhi, Wei, Xiaohui, Jiang, Yinan, Chen, Rong, Li, Qirun, Liang, Ruiying, Zhang, Lijie, Ma, Lizhen, Xia, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960135/
https://ncbi.nlm.nih.gov/pubmed/31969884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02995
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