A Glimpse of the Peptide Profile Presentation by Xenopus laevis MHC Class I: Crystal Structure of pXela-UAA Reveals a Distinct Peptide-Binding Groove

The African clawed frog, Xenopus laevis, is a model species for amphibians. Before metamorphosis, tadpoles do not efficiently express the single classical MHC class I (MHC-I) molecule Xela-UAA, but after metamorphosis, adults express this molecule in abundance. To elucidate the Ag-presenting mechani...

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Bibliographic Details
Published in:J Immunol
Main Authors: Ma, Lizhen, Zhang, Nianzhi, Qu, Zehui, Liang, Ruiying, Zhang, Lijie, Zhang, Bing, Meng, Geng, Dijkstra, Johannes M., Li, Shen, Xia, Max Chun
Format: Artigo
Language:Inglês
Published: AAI 2020
Subjects:
Molecular and Structural Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926391/
https://ncbi.nlm.nih.gov/pubmed/31776204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900865
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