A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Mass spectrometry (MS)-based top-down proteomics provides rich information about proteoforms arising from combinatorial amino acid sequence variations and post-translational modifications (PTMs). Fourier transform ion cyclotron resonance (FT-ICR) MS affords ultra-high resolving power and provides hi...

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發表在:Anal Chem
Main Authors: Tucholski, Trisha, Knott, Samantha, Chen, Bifan, Pistono, Paige, Lin, Ziqing, Ge, Ying
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545233/
https://ncbi.nlm.nih.gov/pubmed/30758949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b04082
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