HDAC inhibition in glioblastoma monitored by hyperpolarized (13)C MRSI.

Vorinostat is a histone deacetylase (HDAC) inhibitor that inhibits cell proliferation and induces apoptosis in solid tumors and is in clinical trials for the treatment of glioblastoma (GBM). The goal of this study was to assess whether hyperpolarized (13)C Magnetic Resonance Spectroscopy (MRS) and M...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Radoul, Marina, Najac, Chloé, Viswanath, Pavithra, Mukherjee, Joydeep, Kelly, Mark, Gillespie, Anne Marie, Chaumeil, Myriam M., Eriksson, Pia, Santos, Romelyn Delos, Pieper, Russell O., Ronen, Sabrina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545173/
https://ncbi.nlm.nih.gov/pubmed/30561869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4044
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