HDAC inhibition in glioblastoma monitored by hyperpolarized (13)C MRSI.

Vorinostat is a histone deacetylase (HDAC) inhibitor that inhibits cell proliferation and induces apoptosis in solid tumors and is in clinical trials for the treatment of glioblastoma (GBM). The goal of this study was to assess whether hyperpolarized (13)C Magnetic Resonance Spectroscopy (MRS) and M...

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Pubblicato in:NMR Biomed
Autori principali: Radoul, Marina, Najac, Chloé, Viswanath, Pavithra, Mukherjee, Joydeep, Kelly, Mark, Gillespie, Anne Marie, Chaumeil, Myriam M., Eriksson, Pia, Santos, Romelyn Delos, Pieper, Russell O., Ronen, Sabrina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545173/
https://ncbi.nlm.nih.gov/pubmed/30561869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4044
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