HDAC inhibition in glioblastoma monitored by hyperpolarized (13)C MRSI.

Vorinostat is a histone deacetylase (HDAC) inhibitor that inhibits cell proliferation and induces apoptosis in solid tumors and is in clinical trials for the treatment of glioblastoma (GBM). The goal of this study was to assess whether hyperpolarized (13)C Magnetic Resonance Spectroscopy (MRS) and M...

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Publicado en:NMR Biomed
Autores principales: Radoul, Marina, Najac, Chloé, Viswanath, Pavithra, Mukherjee, Joydeep, Kelly, Mark, Gillespie, Anne Marie, Chaumeil, Myriam M., Eriksson, Pia, Santos, Romelyn Delos, Pieper, Russell O., Ronen, Sabrina M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545173/
https://ncbi.nlm.nih.gov/pubmed/30561869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4044
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