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Immunoproteasome activation enables human TRIM5α restriction of HIV-1
Type 1 interferon (IFN) suppresses viral replication by upregulating the expression of interferon-stimulated genes (ISGs) with diverse anti-viral properties1. The replication of human immunodeficiency virus type-1 (HIV-1) is naturally inhibited by IFN, with the steps between viral entry and chromoso...
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| Publié dans: | Nat Microbiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6544544/ https://ncbi.nlm.nih.gov/pubmed/30886358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0402-0 |
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