Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

Human myxovirus resistance 2 (MX2/MXB) is an interferon-induced post-entry inhibitor of human immunodeficiency virus type-1 (HIV-1) infection. While the precise mechanism of viral inhibition remains unclear, MX2 is localized to the nuclear envelope, and blocks the nuclear import of viral cDNAs. The...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Dicks, Matthew D. J., Betancor, Gilberto, Jimenez-Guardeño, Jose M., Pessel-Vivares, Lucie, Apolonia, Luis, Goujon, Caroline, Malim, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264145/
https://ncbi.nlm.nih.gov/pubmed/30496303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007408
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados