Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis

Sphingolipids are structural membrane components and important eukaryotic signaling molecules. Sphingolipids regulate inflammation and immunity, and were recently identified as the most differentially abundant metabolite in stool from inflammatory bowel disease (IBD) patients. Commensal bacteria, fr...

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Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Brown, Eric M., Ke, Xiaobo, Hitchcock, Daniel, Jeanfavre, Sarah, Avila-Pacheco, Julian, Nakata, Toru, Arthur, Timothy D., Fornelos, Nadine, Heim, Cortney, Franzosa, Eric A., Watson, Nicki, Huttenhower, Curtis, Haiser, Henry J., Dillow, Glen, Graham, Daniel B., Finlay, B. Brett, Kostic, Aleksandar D., Porter, Jeffrey A., Vlamakis, Hera, Clish, Clary B., Xavier, Ramnik J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544385/
https://ncbi.nlm.nih.gov/pubmed/31071294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.04.002
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