Bacteroides-derived sphingolipids are critical for maintaining intestinal homeostasis and symbiosis

Sphingolipids are structural membrane components and important eukaryotic signaling molecules. Sphingolipids regulate inflammation and immunity, and were recently identified as the most differentially abundant metabolite in stool from inflammatory bowel disease (IBD) patients. Commensal bacteria, fr...

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Pubblicato in:Cell Host Microbe
Autori principali: Brown, Eric M., Ke, Xiaobo, Hitchcock, Daniel, Jeanfavre, Sarah, Avila-Pacheco, Julian, Nakata, Toru, Arthur, Timothy D., Fornelos, Nadine, Heim, Cortney, Franzosa, Eric A., Watson, Nicki, Huttenhower, Curtis, Haiser, Henry J., Dillow, Glen, Graham, Daniel B., Finlay, B. Brett, Kostic, Aleksandar D., Porter, Jeffrey A., Vlamakis, Hera, Clish, Clary B., Xavier, Ramnik J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544385/
https://ncbi.nlm.nih.gov/pubmed/31071294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.04.002
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