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The metabolites NADP(+) and NADPH are the targets of the circadian protein Nocturnin (Curled)

Nocturnin (NOCT) is a rhythmically expressed protein that regulates metabolism under the control of circadian clock. It has been proposed that NOCT deadenylates and regulates metabolic enzyme mRNAs. However, in contrast to other deadenylases, purified NOCT lacks the deadenylase activity. To identify...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Estrella, Michael A., Du, Jin, Chen, Li, Rath, Sneha, Prangley, Eliza, Chitrakar, Alisha, Aoki, Tsutomu, Schedl, Paul, Rabinowitz, Joshua, Korennykh, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542800/
https://ncbi.nlm.nih.gov/pubmed/31147539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10125-z
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