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Crystal Structure of Human Nocturnin Catalytic Domain

Nocturnin (NOCT) helps the circadian clock to adjust metabolism according to day and night activity. NOCT is upregulated in early evening and it has been proposed that NOCT serves as a deadenylase for metabolic enzyme mRNAs. We present a 2.7-Å crystal structure of the catalytic domain of human NOCT....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Estrella, Michael A., Du, Jin, Korennykh, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214945/
https://ncbi.nlm.nih.gov/pubmed/30389976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34615-0
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