Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in dsRNA Response

Viral and endogenous double-stranded RNA (dsRNA) is a potent trigger for programmed RNA degradation by 2–5A/RNase L complex in cells of all mammals. This 2–5A-mediated decay (2–5AMD) is a conserved stress response switching global protein synthesis from homeostasis to production of interferons (IFNs...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Rath, Sneha, Prangley, Eliza, Donovan, Jesse, Demarest, Kaitlin, Wingreen, Ned S., Meir, Yigal, Korennykh, Alexei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754276/
https://ncbi.nlm.nih.gov/pubmed/31494033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.027
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