Dysfunctional peripheral T follicular helper cells dominate in people with impaired influenza vaccine responses: Results from the FLORAH study

Antigen-primed cluster of differentiation (CD) 4(+) T follicular helper (Tfh) cells interact with B cells in the germinal centers (GCs) of lymph nodes to generate vaccine-induced antibody (Ab) responses. In the circulation, peripheral Tfh (pTfh) cells, a subset of memory CD4 T cells, serve as surrog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Biol
Prif Awduron: Pallikkuth, Suresh, de Armas, Lesley R., Rinaldi, Stefano, George, Varghese K., Pan, Li, Arheart, Kristopher L., Pahwa, Rajendra, Pahwa, Savita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542545/
https://ncbi.nlm.nih.gov/pubmed/31100059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000257
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg