Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine

The generation of Ab-secreting plasma cells depends critically on CD4 T-follicular helper (TFH) cells during the germinal center reaction. Germinal center TFH cells share functional properties with circulating CXCR5(+) CD4 T cells, referred to herein as peripheral TFH (pTFH) cells. Because deficient...

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Detalhes bibliográficos
Main Authors: Pallikkuth, Suresh, Parmigiani, Anita, Silva, Sandra Y., George, Varghese K., Fischl, Margaret, Pahwa, Rajendra, Pahwa, Savita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412336/
https://ncbi.nlm.nih.gov/pubmed/22692510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-396648
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