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T Follicular Helper Cells and B Cell Dysfunction in Aging and HIV-1 Infection

T follicular helper (Tfh) cells are a subset of CD4 T cells that provide critical signals to antigen-primed B cells in germinal centers to undergo proliferation, isotype switching, and somatic hypermutation to generate long-lived plasma cells and memory B cells during an immune response. The quantit...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pallikkuth, Suresh, de Armas, Lesley, Rinaldi, Stefano, Pahwa, Savita
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660291/
https://ncbi.nlm.nih.gov/pubmed/29109730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01380
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