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T Follicular Helper Cells and B Cell Dysfunction in Aging and HIV-1 Infection
T follicular helper (Tfh) cells are a subset of CD4 T cells that provide critical signals to antigen-primed B cells in germinal centers to undergo proliferation, isotype switching, and somatic hypermutation to generate long-lived plasma cells and memory B cells during an immune response. The quantit...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660291/ https://ncbi.nlm.nih.gov/pubmed/29109730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01380 |
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