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Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation

Chronic neuroinflammation is known to contributes to the toxicity of neurodegeneration of Parkinson’s disease (PD). However, the molecular and cellular mechanisms controlling inflammatory responses in the central nervous system remain poorly understood. Here we found that a E3 ubiquitin ligase Peli1...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Dai, Dongfang, Yuan, Jia, Wang, Yan, Xu, Jing, Mao, Chaoming, Xiao, Yichuan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541652/
https://ncbi.nlm.nih.gov/pubmed/31142803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44573-w
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