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Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation

Chronic neuroinflammation is known to contributes to the toxicity of neurodegeneration of Parkinson’s disease (PD). However, the molecular and cellular mechanisms controlling inflammatory responses in the central nervous system remain poorly understood. Here we found that a E3 ubiquitin ligase Peli1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dai, Dongfang, Yuan, Jia, Wang, Yan, Xu, Jing, Mao, Chaoming, Xiao, Yichuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541652/
https://ncbi.nlm.nih.gov/pubmed/31142803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44573-w
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