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Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation
Chronic neuroinflammation is known to contributes to the toxicity of neurodegeneration of Parkinson’s disease (PD). However, the molecular and cellular mechanisms controlling inflammatory responses in the central nervous system remain poorly understood. Here we found that a E3 ubiquitin ligase Peli1...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541652/ https://ncbi.nlm.nih.gov/pubmed/31142803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44573-w |
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