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HIV Infection Induces Extracellular Cathepsin B Uptake and Damage to Neurons
HIV-associated neurocognitive disorders prevail in 20–50 percent of infected individuals. Macrophages transmigrate through the blood brain barrier during HIV-1 infection, triggering neuronal dysfunction. HIV-infected macrophages secrete cathepsin B (CATB), and serum amyloid p component (SAPC), induc...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541605/ https://ncbi.nlm.nih.gov/pubmed/31142756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44463-1 |
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