Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Cancer immunotherapy with immune checkpoint inhibitors (CPI) and interleukin (IL)-2 has demonstrated clinical efficacy but is frequently accompanied with severe adverse events caused by excessive and systemic immune system activation. Here, we addressed this need by targeting both the CPI antibodies...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Transl Med
Egile Nagusiak: Ishihara, Jun, Ishihara, Ako, Sasaki, Koichi, Lee, Steve Seung-Young, Williford, John-Michael, Yasui, Mariko, Abe, Hiroyuki, Potin, Lambert, Hosseinchi, Peyman, Fukunaga, Kazuto, Raczy, Michal M., Gray, Laura T., Mansurov, Aslan, Katsumata, Kiyomitsu, Fukayama, Masashi, Kron, Stephen J., Swartz, Melody A., Hubbell, Jeffrey A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541444/
https://ncbi.nlm.nih.gov/pubmed/30971453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau3259
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