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Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing
Laminin, as a key component of the basement membrane extracellular matrix (ECM), regulates tissue morphogenesis. Here, we show that multiple laminin isoforms promiscuously bind to growth factors (GFs) with high affinity, through their heparin-binding domains (HBDs) located in the α chain laminin-typ...
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| Izdano u: | Nat Commun |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986797/ https://ncbi.nlm.nih.gov/pubmed/29867149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04525-w |
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