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Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing

Laminin, as a key component of the basement membrane extracellular matrix (ECM), regulates tissue morphogenesis. Here, we show that multiple laminin isoforms promiscuously bind to growth factors (GFs) with high affinity, through their heparin-binding domains (HBDs) located in the α chain laminin-typ...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Ishihara, Jun, Ishihara, Ako, Fukunaga, Kazuto, Sasaki, Koichi, White, Michael J. V., Briquez, Priscilla S., Hubbell, Jeffrey A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986797/
https://ncbi.nlm.nih.gov/pubmed/29867149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04525-w
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