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The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

During wound healing, the distribution, availability, and signaling of growth factors (GFs) are orchestrated by their binding to extracellular matrix components in the wound microenvironment. Extracellular matrix proteins have been shown to modulate angiogenesis and promote wound healing through GF...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Ishihara, Jun, Ishihara, Ako, Starke, Richard D., Peghaire, Claire R., Smith, Koval E., McKinnon, Thomas A. J., Tabata, Yoji, Sasaki, Koichi, White, Michael J. V., Fukunaga, Kazuto, Laffan, Mike A., Lutolf, Matthias P., Randi, Anna M., Hubbell, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566593/
https://ncbi.nlm.nih.gov/pubmed/30975637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000510
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