Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing

Laminin, as a key component of the basement membrane extracellular matrix (ECM), regulates tissue morphogenesis. Here, we show that multiple laminin isoforms promiscuously bind to growth factors (GFs) with high affinity, through their heparin-binding domains (HBDs) located in the α chain laminin-typ...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ishihara, Jun, Ishihara, Ako, Fukunaga, Kazuto, Sasaki, Koichi, White, Michael J. V., Briquez, Priscilla S., Hubbell, Jeffrey A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986797/
https://ncbi.nlm.nih.gov/pubmed/29867149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04525-w
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