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Towards the preparation of synthetic outer membrane vesicle models with micromolar affinity to wheat germ agglutinin using a dialkyl thioglycoside

A series of alkyl thioglycosides and alkyl thiodiglycosides bearing glucose and N-acetylglucosamine residues were prepared by thiol–ene coupling in moderate to good yields (40–85%). Their binding ability towards wheat germ agglutinin was measured by competitive enzyme-linked lectin assays. One of th...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Fayolle, Dimitri, Berthet, Nathalie, Doumeche, Bastien, Renaudet, Olivier, Strazewski, Peter, Fiore, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541351/
https://ncbi.nlm.nih.gov/pubmed/31164930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.90
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