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Towards the preparation of synthetic outer membrane vesicle models with micromolar affinity to wheat germ agglutinin using a dialkyl thioglycoside

A series of alkyl thioglycosides and alkyl thiodiglycosides bearing glucose and N-acetylglucosamine residues were prepared by thiol–ene coupling in moderate to good yields (40–85%). Their binding ability towards wheat germ agglutinin was measured by competitive enzyme-linked lectin assays. One of th...

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Vydáno v:Beilstein J Org Chem
Hlavní autoři: Fayolle, Dimitri, Berthet, Nathalie, Doumeche, Bastien, Renaudet, Olivier, Strazewski, Peter, Fiore, Michele
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541351/
https://ncbi.nlm.nih.gov/pubmed/31164930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.90
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