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Therapeutic approaches to target alpha-synuclein pathology

Starting two decades ago with the discoveries of genetic links between alpha-synuclein and Parkinson’s disease risk and the identification of aggregated alpha-synuclein as the main protein constituent of Lewy pathology, alpha-synuclein has emerged as the major therapeutic target in Parkinson’s disea...

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Bibliographic Details
Published in:Exp Neurol
Main Authors: Brundin, Patrik, Dave, Kuldip D., Kordower, Jeffrey H.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541231/
https://ncbi.nlm.nih.gov/pubmed/28987463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.10.003
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