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Sorting Out Release, Uptake and Processing of Alpha-Synuclein During Prion-Like Spread of Pathology

Parkinson’s disease is a progressive neurological disorder that is characterized by the formation of intracellular protein inclusion bodies composed primarily of a misfolded and aggregated form of the protein α-synuclein. There is growing evidence that supports the prion-like hypothesis of α-synucle...

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Détails bibliographiques
Publié dans:J Neurochem
Auteurs principaux: Tyson, Trevor, Steiner, Jennifer A., Brundin, Patrik
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958606/
https://ncbi.nlm.nih.gov/pubmed/26617280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13449
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