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Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room

Alpha-synuclein is an intrinsically disordered, highly dynamic protein that pathogenically aggregates into inclusion structures called Lewy bodies, in several neurogenerative diseases termed synucleinopathies. Despite its importance for understanding disease, the oligomerization status of alpha-synu...

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Bibliografski detalji
Izdano u:NPJ Parkinsons Dis
Glavni autori: Killinger, Bryan A., Melki, Ronald, Brundin, Patrik, Kordower, Jeffrey H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851126/
https://ncbi.nlm.nih.gov/pubmed/31728405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-019-0095-3
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