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Topological Analysis of the Type 3 Secretion System Translocon Pore Protein IpaC following Its Native Delivery to the Plasma Membrane during Infection

Many Gram-negative bacterial pathogens require a type 3 secretion system (T3SS) to deliver effector proteins into eukaryotic cells. Contact of the tip complex of the T3SS with a target eukaryotic cell initiates secretion of the two bacterial proteins that assemble into the translocon pore in the pla...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Russo, Brian C., Duncan, Jeffrey K., Goldberg, Marcia B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538787/
https://ncbi.nlm.nih.gov/pubmed/31138750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00877-19
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