IpaD of Shigella flexneri Is Independently Required for Regulation of Ipa Protein Secretion and Efficient Insertion of IpaB and IpaC into Host Membranes

Shigella flexneri causes human dysentery after invading the cells of the colonic epithelium. The best-studied effectors of Shigella entry into colonocytes are the invasion plasmid antigens IpaC and IpaB. These proteins are exported via a type III secretion system (TTSS) to form a pore in the host me...

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Hlavní autoři: Picking, Wendy L., Nishioka, Hiroaki, Hearn, Patricia D., Baxter, M. Aaron, Harrington, Amanda T., Blocker, Ariel, Picking, William D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064949/
https://ncbi.nlm.nih.gov/pubmed/15731041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1432-1440.2005
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